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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDC1
All Species:
8.79
Human Site:
S516
Identified Species:
27.62
UniProt:
Q14676
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14676
NP_055456.2
2089
226666
S516
H
L
E
R
S
Q
A
S
T
T
V
D
I
N
T
Chimpanzee
Pan troglodytes
Q7YR40
2171
235369
S516
H
L
E
R
S
Q
A
S
T
T
V
D
I
N
T
Rhesus Macaque
Macaca mulatta
Q5TM68
2173
235100
S518
H
L
E
R
S
Q
A
S
I
T
V
D
I
N
T
Dog
Lupus familis
XP_532059
1271
139834
Cat
Felis silvestris
Mouse
Mus musculus
Q5PSV9
1707
184652
P205
S
D
E
E
V
S
S
P
A
P
S
V
P
G
P
Rat
Rattus norvegicus
Q5U2M8
1279
136930
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510738
863
91291
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_698304
1913
212679
H411
P
V
S
S
G
D
L
H
L
E
S
D
T
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.1
88.7
30.1
N.A.
50.3
36.9
N.A.
23.3
N.A.
N.A.
21
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.4
90.9
41
N.A.
60.4
45.7
N.A.
29
N.A.
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
6.6
0
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
0
N.A.
13.3
0
N.A.
0
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
38
0
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
13
0
0
0
0
0
50
0
13
0
% D
% Glu:
0
0
50
13
0
0
0
0
0
13
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
0
0
0
0
0
0
0
0
13
0
% G
% His:
38
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
0
0
0
38
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
38
0
0
0
0
13
0
13
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
38
0
% N
% Pro:
13
0
0
0
0
0
0
13
0
13
0
0
13
0
13
% P
% Gln:
0
0
0
0
0
38
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
13
13
38
13
13
38
0
0
25
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
25
38
0
0
13
0
38
% T
% Val:
0
13
0
0
13
0
0
0
0
0
38
13
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _